@article {4774,
	title = {EVALUATION OF THE ANALYTICAL VALUE OF SARS-CoV-2 ANTIGEN TEST IN RELATION TO Ct-VALUES OF RT-qPCR IN PATIENTS SUSPECTED OF COVID-19},
	journal = {Mak Med Pregled},
	volume = {75},
	year = {2021},
	pages = {10-13},
	abstract = {Introduction. COVID-19 pandemic threatens global human health. Reverse-transcription quantitative polymerase chain reaction (RT-qPCR) is a reference test for identification of acute SARS-CoV-2 infection, but it is associated with results delay. There is a need of fast and reliable tests which can improve the efforts of controlling the transmission of SARS-CoV-2. Aim. The aim of this study was to determine the analytical value of the rapid SARS-CoV-2 Ag-test in relation to the Ct values of the RT-qPCR. Methods. The study group comprised outpatients suspected for COVID-19, sampled twice, first for the routine RT-qPCR, and second for SARS-CoV-2 antigen testing. The results obtained by the rapid antigen test (Panbio{\texttrademark} COVID-19) were evaluated in relation to Ct values of the SARS-CoV-2 E-gene, obtained by RTqPCR Allplex 19-nCoV multiplex assay platform. Results. SARS-CoV-2 prevalence, based on RT-qPCR, was 50.8\% (186/366). Specificity of the PanbioTM COVID- 19 Ag Rapid Test was 100\%. Test sensitivity was 73.8\%. Restricting RT-qPCR to Ct-values\&lt;30 increased test sensitivity to 91.2\%. Conclusion. The findings underscored the epidemiological value of the rapid Ag-test since it reliably identifies contagious SARS-CoV-2 infected individuals who actively spread the virus in the community.},
	url = {https://repository.ukim.mk/bitstream/20.500.12188/24573/1/MMP202175\%281\%29-15-18.pdf},
	author = {Gorica Popova and Katerina Boskoska and Ivana Arnaudova-Danevska and Katerina Blagoevska}
}
