Publications

Background: The problem of venous ulcers and chronic venous insufficiency is quite common in dermatological clinics. Every day, we face challenges regarding treatment and prognosis. As the patients are more often over fifty years of age, with more comorbidities, and at the very beginning of treatment, we already have an idea of how the entire process of epithelization of the ulcers may take place. Materials and Methods: A total of 105 patients with chronic venous insufficiency and venous ulcers were included in the study. Each was followed for more than twelve weeks. Patients with hypertension, diabetes mellitus, and thrombophlebitis were analyzed separately. Results: Patients with an ulcer closure time of twelve weeks and longer had a high blood pressure more often. Diabetics with venous ulcers on the lower extremities more often had delayed ulcer healing. A statistically significant difference was confirmed in the distribution of the patients with and without thrombophlebitis. Conclusion: The existence of comorbidities, such as hypertension, diabetes mellitus, and thrombosis, may affect the healing process of venous ulcers, yet thrombosis proved to be the most important factor. Key words: Venous Ulcers; Diabetes Mellitus; Thrombosis; Hypertension

Introduction: Thrombophilia is a condition of increased possibility of thrombs formation. Due to hormonal changes and the fetus in pregnant women there is an increased risk of thrombosis, in combination with thrombophilia can lead to fetal loss. Selective thrombophilia screening based on previous personal and/or family history of venous thromboembolism is cost-effective and can prevent some complications like fetal loss, and gestational complications. Case Report: We are presenting two pregnant women with family history of thrombosis and venous disease and previously gestational complications. Discussion: Patients without a personal history of venous disease but with a family history of the same, and with complications of pregnancy in the form of miscarriage, IUGR and stillbirth, should be examined. Screening in these women will help prevent further complications. Conclusion: From our experience we can conclude that in women with complications in pregnancy and a positive history of venous disease should be considered into account the existence of thrombophilia. Diagnosing early also means starting thromboprophylaxis sooner which lead to increasing better maternal and perinatal outcomes.

Introduction: Hair loss in women is much rarer compared to the male field. Due to the accepted social norms for the appearance of a woman, where she is expected to have thick and long hair, women who have a problem with hair loss face a much bigger problem than what is visible at first glance. Case report: We present 3 cases of women with hair loss, aged from 28 to 37 years. They all complain of increased hair loss and thinning of the central scalp. We decided to try the treatment which consists of 3 mesotherapies and 3 PRP hair treatments. Disscusion: Hair loss can be the result of heredity, hormonal changes, medical conditions or a normal part of aging. Mesotherapy can help to reduce hair fall and treat hair loss problems with advanced and minimally-invasive methods. PRP is an excellent treatment for impaired hair growth. Conclusion: This combination of treatments is completely safe for the patients, with minimal side effects. We obtained satisfactory results in all three patients.

Background: The biggest challenge in patients with chronic venous insufficiency is venous ulcers that occur in stage 6 of the CEAP classification. In general, acute ulcers have a 71–80% chance of healing, while chronic ulcers only have a 22% chance of healing. Our clinical practice has shown that patients diagnosed with peripheral arterial occlusive disease have a much longer duration of the disease and a more difficult treatment of venous ulcers than patients with normal arterial circulation. Materials and Methods: The study included 105 patients with CVI and a developed leg ulcer. Among these, twenty patients were diagnosed with peripheral arterial occlusive disease. All patients were followed for more than twelve weeks. Results: Peripheral arterial occlusive disease was significantly more common in patients with delayed healing than in patients with normal venous ulcer healing: 18 (30%) vs. 2 (4.4%). for twelve weeks or longer, and it was statistically significant for p = 0.00097. Conclusion: Peripheral arterial occlusive disease has been shown to be an important indicator of venous epithelial wound healing. The establishment of good arterial circulation is closely related to the course of treatment of chronic venous ulcers.

Целта на овој труд е да се истражи можноста правни лица да се јавуваат како даватели на издршка во рамки на договорот за доживотна издршка, преку анализа на правните решенија во повеќе европски правни системи. Истражувањето се заснова на компаративна анализа на релевантните законодавства, со посебен фокус на Србија, Хрватска, Швајцарија, Унгарија и Франција. Преку анализа на позитивното право, судска пракса и понови законски реформи, трудот идентификува отсуство на јасна и хармонизирана регулатива за учество на правни лица, што создава ризици од правна несигурност и можни злоупотреби. Во услови на стареење на населението и зголемена улога на институционалната грижа, трудот ја препознава потребата од воспоставување прецизна правна рамка која ќе утврди кои правни лица можат да бидат даватели на издршка, под кои услови, и со какви гаранции за заштита на старите лица, со цел да се обезбеди правна сигурност, транспарентност и достоинствен третман на примателите на издршката.Клучни зборови: договор за доживотна издршка, правни лица, компаративна анализа, правна сигурност.

The monitoring of employees is an issue closely related to the right toprivacy, protection of personal data, and dignity. The development of modern technol-ogy has brought many benefits, but also risks – to which special attention should bepaid, especially with the installation of video surveillance systems. The data collectedduring video surveillance is usually images relating to an identified person, or a personwho can be identified – directly or indirectly – to monitor behaviour. As video monitoringspreads, people’s freedom of movement and behaviour, and their privacy, are thereforereduced. Video surveillance is used for various purposes, but mostly for security - whereguarantees must be taken to avoid any misuse for completely different and individualpurposes (e.g. for marketing; to monitor the work of employees, etc.). This paper providesan analysis of the rules and regulations in Macedonian legislation. Special attention ispaid to the procedure and circumstances under which it is possible to install permanentvideo surveillance to control work activity.KEYWORDS: video surveillance, workplace, data protection, procedure.

Abstract Coloboma of the uvea is a relatively rare ophthalmic entity, which occurs as a result of a disturbance in the process of closing the embryonic optic fissure. It can be hereditary, sporadic or part of systemic syndromes. Each of the structures of the uveal tract, alone or together, unilaterally or bilaterally, can have the presence of a coloboma. In this paper, we describe the case of a 9-year-old girl with bilateral coloboma and accompanying ectrodactyly of the lower limbs, probably as part of a syndrome - Ectrodactyly-ectodermal dysplasia-cleft syndrome. The patient is regularly monitored with biomicroscopic and funduscopic examination supplemented with posterior optical coherence tomography and perimetry, with the aim of timely recognition of possible ophthalmic complications. Keywords: coloboma, uvea, ectrodactyly, congenital malformation

The basic demographic characteristics of one society are tightly related to the youth’s potential as the core for any future social development. The prospects in Balkan countries are jeopardized by low fertility and continued migration which intensified in the last decades. Migration in the past was generated by wars, political instability, and a lack of economic prospects. Today, a vast part of the region is integrated into the EU, and the rest is with clear aspirations to integrate in the near future. However, some open questions as dysfunctional political systems, corruption, not having a rule of law, and economic instability are some of the main reasons for future migration.This article is focused on the general motivation for migration in the Balkan countries, with a focus on Macedonian society. Two surveys are presented as an empirical basis for further analyses. The results reflect the general situation in the eastern and central regions of the Republic of N. Macedonia. Longitudinal aspects are included, comparing the data generated in 2014, 2018, 2022, and 2023. Additionally, the official statistics confirm the thesis and create broader picture for the correlative relations between educational motivation and migration trends.

Членот 25 од Повелбата за фундаментални права на ЕУ ги признава правата и заштитата на старите лица, овој труд има за цел да елаборира дали договорот за доживотна издршка може да се користи како правен инструмент за да се обезбеди ефективно спроведување на член 25. Во првиот дел, овој труд ќе ги анализира можните учесници/страни во договорот за доживотна издршка vis-a-vis субјектот/ите кои се одговорни за обезбедување на ефективна заштита на правата на старите лица според член 25 од CFREU. Конкретно, написот ќе анализира кој може да биде субјект на договорот vis-à-vis, кој е одговорен за обезбедување на ефективно на правата и заштита на старите лица. Во вториот дел од трудот ќе го анализираме вториот проблем поврзан со потребата од подобрување на правната заштита на старите лица кои се вклучени во овие договори. Недостигот од правно знаење кај овие луѓе често резултира со неправилно разбирање на нивните права и обврски, што може да доведе до непредвидени последици кога станува збор за издршката и имотните прашања. Во многу случаи, постарите лица можеби не се свесни дека имаат право на правна помош или не можат да си дозволат да чекаат судски одлуки поради нивната возраст. Конечно, третиот дел од трудот ќе се занимава со регулирање на договорот за доживотна издршка во земјите членки на ЕУ и како тој е регулиран во правните системи. Овој труд ќе даде анализа на правната рамка, судските одлуки, за да се види кои субјекти се појавуваат кај овој вид на договори и кои се нивните права и обврски. Компаративниот метод ќе се примени за да се истражи регулирањето на овој договор во земјите-членки на ЕУ и да се утврди дали истиот е доследно регулиран. Главната цел е да се идентификуваат разликите и сличностите меѓу различните правни системи и нивната заштита на правата на старите лица. Во овој труд ќе бидат предложени и препораки за подобрување на уредувањето на овој правен институт. Клучни зборови: Договори за доживотна издршка, права на стари лица, член 25, CFREU, правна заштита, земји членки на ЕУ, компаративна анализа, правна регулатива.